Chair in Experimental Therapeutics
Dr. Muti is Professor and Dofasco Chair in Experimental Cancer Therapeutics in the Department of Oncology at McMaster University. She was the Scientific Director of the Italian National Cancer Institute (NCI) "Regina Elena" in Rome, Italy and adjunct Professor of Epidemiology at the Harvard School of Public Health. She held the position of Chair of the Department of Epidemiology at the NCI in Rome, and prior to that she held the position of tenured Full Professor of Epidemiology in the Department of Social and Preventive Medicine, University of Buffalo, State University of New York.
Over the past twenty years much of her scientific work has focused on epidemiological methods, particularly focusing on the use of biomarkers in population-based studies and cancer epidemiology. She has investigated metholological questions related to application of biomarkers in chronic disease epidemiology, conducted translational studies and explored sources of variation in biomarkers. She has received national and international recognition for her work using biological specimen banks.
In the field of cancer research, her major scientific research has been the etiological relation of hormones to breast and prostate cancer. Currently, her major research area is cancer genomics-translational research with a focus on cancer prevention.
Muti P, Sacconi A, Hossain A, Donzelli S, Bossel Ben Moshe N, Ganci F, Sieri S, Krogh V, Berrino F, Biagioni F, Strano S, Beyene J, Yarden Y, Blandino G. Down regulation of micriRNAs 145-3p and 145-5p is a long-term predictor of postmenopausal breast cancer risk: the ORDET prospective study Cancer Epidemiol Biomarkers Prev. 2014 Jul 29. pii: cebp.0398.20
Goeman F, De Nicola F, Meo PD, Pallocca M, Elmi B, Castrignanò T, Pesole G, Strano S, Blandino G, Fanciulli M, Muti P. VDR Primary targets by genome-wide transriptional profiling J Steroid Biochem Mol Biol. 2014 Apr 9
Contiero P, Berrino F, Tagliablue G, Mastroianni A, Di Mauro MG, Fabiano S, Annulli M, Muti P. “Fasting blood glucose and long-term prognosis of non-metastatic breast cancer: A cohort study.” Breast Cancer Research and Treatment. 138(3):951-9; Apr 2013. Epub Apr 9, 2013.
Schernhammer E, Pasanisi P, Krogh V, Blandino G, Berrino F, Muti P. “Sex hormones and breast cancer development in premenopausal women: The ORDET cohort study.” Breast Cancer Research 2013 Jun 18;15(3)